Sheena's white parents are killed while on Safari. She is raised by the mystical witch woman of an African tribe. When her foster mother is framed for the murder of a political leader, Sheena and a newsman, Vic Casey are forced to flee while pursued by the mercenaries hired by the real killer, who hopes to assume power. Sheena's ability to talk to the animals and knowledge of jungle lore give them a chance against the high tech weapons of the mercenaries. This is the story of Sheena whose white parents are killed while on Safari. She is raised by the mystical witch woman of an African tribe. As Sheena grows up, she learns much from the Shaman about the lore of the jungle and the ways of all its creatures and is even entrusted with the secret of telepathic communication with the animals. Outsiders rarely disturb their territory, since that part of Tigora is under the special protection of King Jabalani. But trouble is brewing in Tigora; the King's ex-football champion younger brother Prince Otwani is conspiring with his brother's fiancee, Countess Zanda, to have Jabalani assassinated so that they can exploit the titanium-rich Zambouli lands. Experiencing a vision foretelling the death of the King, the Shaman hastens to Tigora's capital of Azan to try and warn him, but is arrested by corrupt police officers working for Zanda. Otwani's old "friend", reporter Vic Casey, and his cameraman Fletch Agronsky are in Tigora to do a story on the former football player. When King Jabalani is killed and the Shaman is framed for it, Vic and Fletch realize they are on to a much bigger story than they had anticipated. Heading to a remote prison compound to interview the Shaman they bear witness to her rescue by Sheena and her animal friends: "Chango", an elephant; "Marika", a zebra; and "Tiki", a chimpanzee.